SPECTAZOLE (econazole nitrate 1%) Cream 631-11-331-1 For … - MywallpapersMobi

SPECTAZOLE (econazole nitrate 1%) Cream 631-11-331-1 For …


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Spectazole Cream

GENERIC NAME(S): Econazole

Read Reviews (5) Find Lowest Prices

  • Uses
  • Side Effects
  • Precautions
  • Interactions
  • Overdose
  • Images
Uses

Uses

Econazole is used to treat a variety of fungal skin infections such as athlete’s foot , jock itch , and ringworm . This medication is also used to treat a skin condition known as pityriasis ( tinea versicolor ), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Econazole is an azole antifungal that works by preventing the growth of fungus .

How to use Spectazole Cream

Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply this medication on and around the affected area as directed by your doctor, usually once or twice a day. The dosage and length of treatment depend on the type of infection being treated. Do not apply this medication more often or use for longer than prescribed.

Wash your hands after using unless the area being treated includes the hands. Do not wrap, cover, or bandage the area unless directed to do so by your doctor.

Do not apply this medication in the eyes , nose, or mouth , or inside the vagina . If you do get the medication in those areas, flush with plenty of water.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

Tell your doctor if your condition lasts after 2 weeks of treatment (or after 4 weeks of treatment for athlete’s foot ) or if it gets worse.

Related Links

What conditions does Spectazole Cream treat?

Find Lowest Prices


Read More

Side Effects

Side Effects

Burning, stinging, irritation, or redness at the application site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: rash , itching /swelling (especially of the face/ tongue /throat), severe dizziness , trouble breathing .

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US –

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Related Links

List Spectazole Cream side effects by likelihood and severity.

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Read More

Precautions

Precautions

Before using econazole , tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (such as clotrimazole , ketoconazole , miconazole ); or if you have any other allergies . This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication , tell your doctor or pharmacist your medical history.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs , nonprescription drugs, and herbal products).

During pregnancy , this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

It is unknown if this drug passes into breast milk. Consult your doctor before breast -feeding.

Related Links

What should I know regarding pregnancy, nursing and administering Spectazole Cream to children or the elderly?

Find Lowest Prices


Read More

Interactions

Interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions . Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist . Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Find Lowest Prices


Read More

Overdose

Overdose

This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

Notes

Do not share this medication with others.

This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor tells you to.

When treating pityriasis, this medication may not cause a return to normal skin color right away. It may take several months after treatment is completed for your natural skin color to return.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised October 2017. Copyright(c) 2017 First Databank, Inc.

Find Lowest Prices


Read More

Images

Sorry. No images are available for this medication.

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    Skip to main content

    Spectazole Cream

    GENERIC NAME(S): Econazole

    Read Reviews (5) Find Lowest Prices

    • Uses
    • Side Effects
    • Precautions
    • Interactions
    • Overdose
    • Images
    Uses

    Uses

    Econazole is used to treat a variety of fungal skin infections such as athlete’s foot , jock itch , and ringworm . This medication is also used to treat a skin condition known as pityriasis ( tinea versicolor ), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs. Econazole is an azole antifungal that works by preventing the growth of fungus .

    How to use Spectazole Cream

    Use this medication on the skin only. Clean and thoroughly dry the area to be treated. Apply this medication on and around the affected area as directed by your doctor, usually once or twice a day. The dosage and length of treatment depend on the type of infection being treated. Do not apply this medication more often or use for longer than prescribed.

    Wash your hands after using unless the area being treated includes the hands. Do not wrap, cover, or bandage the area unless directed to do so by your doctor.

    Do not apply this medication in the eyes , nose, or mouth , or inside the vagina . If you do get the medication in those areas, flush with plenty of water.

    Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time(s) each day.

    Continue to use this medication until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

    Tell your doctor if your condition lasts after 2 weeks of treatment (or after 4 weeks of treatment for athlete’s foot ) or if it gets worse.

    Related Links

    What conditions does Spectazole Cream treat?

    Find Lowest Prices


    Read More

    Side Effects

    Side Effects

    Burning, stinging, irritation, or redness at the application site may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction , including: rash , itching /swelling (especially of the face/ tongue /throat), severe dizziness , trouble breathing .

    This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

    In the US –

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

    In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

    Related Links

    List Spectazole Cream side effects by likelihood and severity.

    Find Lowest Prices


    Read More

    Precautions

    Precautions

    Before using econazole , tell your doctor or pharmacist if you are allergic to it; or to other azole antifungals (such as clotrimazole , ketoconazole , miconazole ); or if you have any other allergies . This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

    Before using this medication , tell your doctor or pharmacist your medical history.

    Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs , nonprescription drugs, and herbal products).

    During pregnancy , this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

    It is unknown if this drug passes into breast milk. Consult your doctor before breast -feeding.

    Related Links

    What should I know regarding pregnancy, nursing and administering Spectazole Cream to children or the elderly?

    Find Lowest Prices


    Read More

    Interactions

    Interactions

    Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions . Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist . Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

    Find Lowest Prices


    Read More

    Overdose

    Overdose

    This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center.

    Notes

    Do not share this medication with others.

    This medication has been prescribed for your current condition only. Do not use it later for another infection unless your doctor tells you to.

    When treating pityriasis, this medication may not cause a return to normal skin color right away. It may take several months after treatment is completed for your natural skin color to return.

    Missed Dose

    If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Use your next dose at the regular time. Do not double the dose to catch up.

    Storage

    Store at room temperature. Keep all medications away from children and pets.

    Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised October 2017. Copyright(c) 2017 First Databank, Inc.

    Find Lowest Prices


    Read More

    Images

    Sorry. No images are available for this medication.

    Previous:
    Next: Side Effects

    More Resources for Spectazole Cream

    • Find Lowest Prices on
    • Check Interactions
    • Read Reviews (5)
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      • Zoloft
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      • Heavy Sweating Could Be a Medical Problem
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      Find More Drugs Used to Treat these Conditions

      • fungal infection of the skin with yellow patches
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      • ringworm of the body
      • ringworm of groin area
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      • Inflammation and Infection of Nail Cuticle
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      Spectazole

      • Generic Name: econazole nitrate
      • Brand Name: Spectazole
      Last reviewed on RxList: 7/2/2018

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      Drug Description

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      SPECTAZOLE
      (econazole nitrate 1%) Cream

      For Topical Use Only

      DESCRIPTION

      SPECTAZOLE Cream contains the antifungal agent , econazole nitrate 1%, in a water-miscible base consisting of pegoxol 7 stearate, peglicol 5 oleate, mineral oil , benzoic acid, butylated hydroxyanisole, and purified water. The white to off-white soft cream is for topical use only.

      Chemically, econazole nitrate is 1-[2-(4-chloro-phenyl) methoxy-2-(2,4-dichlorophenyl)ethyl]- 1H-imidazole mononitrate. Its structure is as follows:

      SPECTAZOLE (econazole nitrate) Structural Formula Illustration

      Indications & Dosage

      INDICATIONS

      SPECTAZOLE Cream is indicated for topical application in the treatment of tinea pedis, tinea cruris , and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes,  Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis , and in the treatment of tinea versicolor.

      DOSAGE AND ADMINISTRATION

      Sufficient SPECTAZOLE Cream should be applied to cover affected areas once daily in patients with tinea pedis, tinea cruris, tinea corporis, and tinea versicolor, and twice daily (morning and evening) in patients with cutaneous candidiasis.

      Early relief of symptoms is experienced by the majority of patients and clinical improvement may be seen fairly soon after treatment is begun; however, candidal infections and tinea cruris and corporis should be treated for two weeks and tinea pedis for one month in order to reduce the possibility of recurrence. If a patient shows no clinical improvement after the treatment period, the diagnosis should be redetermined. Patients with tinea versicolor usually exhibit clinical and mycological clearing after two weeks of treatment.

      HOW SUPPLIED

      SPECTAZOLE (econazole nitrate 1%) Cream is supplied in tubes of 15 grams (NDC 0259-5460-02), 30 grams (NDC 0259-5460-01), and 85 grams (NDC 0259-5460-03).

      Store SPECTAZOLE Cream below 86°F.

      Merz Pharmaceuticals, LLC, Greensboro, NC 27410. Revised: Feb 2014

      Side Effects & Drug Interactions

      SIDE EFFECTS

      During clinical trials, approximately 3% of patients treated with econazole nitrate 1% cream reported side effects thought possibly to be due to the drug, consisting mainly of burning, itching, stinging, and erythema . One case of pruritic rash has also been reported.

      DRUG INTERACTIONS

      Warfarin

      Concomitant administration of econazole and warfarin has resulted in enhancement of anticoagulation effect.  Most cases reported product application with use under occlusion , genital application, or application to large body surface area which may increase the systemic absorption of econzole nitrate.  Monitoring of International Normalized Ratio (INR) and/or prothrombin time may be indicated especially for patients who apply econazole to large body surface areas, in the genital area, or under occlusion.

      Warnings & Precautions

      WARNINGS

      SPECTAZOLE is not for ophthalmic use.

      PRECAUTIONS

      General

      If a reaction suggesting sensitivity or chemical irritation should occur, use of the medication should be discontinued.

      For external use only. Avoid introduction of SPECTAZOLE Cream into the eyes.

      Carcinogenicity Studies

      Long-term animal studies to determine carcinogenic potential have not been performed.

      Fertility (Reproduction)

      Oral administration of econazole nitrate in rats has been reported to produce prolonged gestation. Intravaginal administration in humans has not shown prolonged gestation or other adverse reproductive effects attributable to econazole nitrate therapy.

      Pregnancy

      Pregnancy Category C. Econazole nitrate has not been shown to be teratogenic when administered orally to mice, rabbits or rats. Fetotoxic or embryotoxic effects were observed in Segment I oral studies with rats receiving 10 to 40 times the human dermal dose. Similar effects were observed in Segment II or Segment III studies with mice, rabbits and/or rats receiving oral doses 80 or 40 times the human dermal dose.

      Econazole nitrate should be used in the first trimester of pregnancy only when the physician considers it essential to the welfare of the patient. The drug should be used during the second and third trimesters of pregnancy only if clearly needed.

      Nursing Mothers

      It is not known whether econazole nitrate is excreted in human milk. Following oral administration of econazole nitrate to lactating rats, econazole and/or metabolites were excreted in milk and were found in nursing pups. Also, in lactating rats receiving large oral doses (40 or 80 times the human dermal dose), there was a reduction in post partum viability of pups and survival to weaning; however, at these high doses, maternal toxicity was present and may have been a contributing factor. Caution should be exercised when econazole nitrate is administered to a nursing woman.

      Overdosage & Contraindications

      OVERDOSE

      Overdosage of econazole nitrate in humans has not been reported to date. In mice, rats, guinea pigs and dogs, the oral LD 50 values were found to be 462, 668, 272, and >160 mg/kg, respectively.

      CONTRAINDICATIONS

      SPECTAZOLE Cream is contraindicated in individuals who have shown hypersensitivity to any of its ingredients.

      Clinical Pharmacology

      CLINICAL PHARMACOLOGY

      After topical application to the skin of normal subjects, systemic absorption of econazole nitrate is extremely low. Although most of the applied drug remains on the skin surface, drug concentrations were found in the stratum corneum which, by far, exceeded the minimum inhibitory concentration for dermatophytes. Inhibitory concentrations were achieved in the epidermis and as deep as the middle region of the dermis . Less than 1% of the applied dose was recovered in the urine and feces.

      Microbiology

      Econazole nitrate has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections as described in the INDICATIONS AND USAGE section.

      Dermatophytes

      Epidermophyton floccosum
      Trichophyton mentagrophytes

      Microsporum audouini
      Trichophyton rubrum

      Microsporum canis
      Trichophyton tonsurans

      Microsporum gypseum

      Yeasts

      Candida albicans
      Malassezia furfur

      Econazole nitrate exhibits broad-spectrum antifungal activity against the following organisms in vitro, but the clinical significance of these data is unknown,

      Dermatophytes

      Trichophyton verrucosum

      Yeasts

      Candida guillermondii
      Candida parapsilosis

      Candida tropicalis

      Medication Guide

      PATIENT INFORMATION

      No information provided. Please refer to the WARNINGS and PRECAUTIONS sections.

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