High MCHC: Causes and Treatment - MywallpapersMobi

High MCHC: Causes and Treatment

MCHC | definition of MCHC by Medical dictionary

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MCHC

Also found in: Dictionary , Thesaurus , Legal , Acronyms , Encyclopedia .

Related to MCHC: RDW

concentration

 [kon″sen-tra´shun]

1. increase in strength by evaporation.
2. the ratio of the mass or volume of a solute to the mass or volume of the solution or solvent.
3. intense mental focus.
hydrogen ion concentration see hydrogen ion concentration .
mass concentration the mass of a constituent substance divided by the volume of the mixture, as milligrams per liter (mg/l).
mean corpuscular hemoglobin concentration (MCHC) the average hemoglobin concentration in erythrocytes, conventionally expressed in “per cent,” meaning grams per deciliter of red blood cells, obtained by dividing the blood hemoglobin concentration (in g/dl) by the hematocrit (in l/l): MCHC = Hb/Hct.
minimal alveolar concentration (MAC) the concentration of anesthetic that at a pressure of 1 atmosphere produces immobility in 50 per cent of subjects exposed to a noxious stimulus.
minimal bactericidal concentration (MBC) the lowest concentration of a given antibiotic required to kill a specific organism.
minimal inhibitory concentration (MIC) the lowest concentration of a given antibiotic that inhibits the growth of a specific organism.
molar concentration the concentration of a substance expressed in terms of molarity .
concentration test a test of renal function based on the patient’s ability to concentrate urine; see also fishberg concentration test .

MCHC

Abbreviation for mean corpuscular hemoglobin concentration .

MCHC

mean corpuscular hemoglobin concentration.

MCHC

abbreviation for mean cell hemoglobin concentration .

MCHC

Mean corpuscular/cell haemoglobin concentration. The amount of haemoglobin in an average-sized erythrocyte. MCHC is a value derived on automated (e.g., Coulter) cell counters from measured parameters.
 
Ref range
31–36 g/dl.

MCHC

Mean corpuscular/cell hemoglobin concentration A value derived on automated cell counters from measured parameters Ref range 31-36 g/dl

MCHC

Abbreviation for mean corpuscular hemoglobin concentration.

Mean corpuscular hemoglobin concentration (MCHC)

The measurement of the average concentration of hemoglobin in a red blood cell.
Mentioned in: Red Blood Cell Indices

MCHC

Abbreviation for mean corpuscular hemoglobin concentration.

MCHC,

n See mean corpuscular hemoglobin concentration .

MCHC

mean corpuscular hemoglobin concentration, an expression of the average percentage hemoglobin concentration obtained by multiplying the hemoglobin in grams by 100 and dividing by the hematocrit determination.

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Mentioned in
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  • Anemia
  • anemia of chronic disease
  • aplastic anemia
  • autoimmune hemolytic anemia
  • Blackfan-Diamond anemia
  • blood count
  • Colour Index
  • Complete Blood Count, Hemoglobin
  • Complete Blood Count, RBC Indices
  • concentration
  • concentration test
  • congenital hypoplastic anemia
  • Cooley’s anemia
  • deficiency anemia
  • Diamond-Blackfan anemia
  • Diamond-Blackfan syndrome
  • drug-induced immune hemolytic anemia
  • erythrocyte
  • erythrocyte count

References in periodicals archive
?

1c]; MCH, mean corpuscular hemoglobin; MCV, mean corpuscularvolume; MCHC, mean corpuscular hemoglobin concentration; JDS, Japan Diabetes Society; NGSP, National Glycohemoglobin Standardization Program; eGFR, estimated glomerular filtration rate; eAG, estimated average glucose; JDS/JSCC, Japanese Diabetes Society and Japanese Society for Clinical Chemistry; NGSP, US National Glycohemoglobin Standardization Program.

As compared to the Western study, MCHC mean values were lower than that observed in 6 month, 9 month and one year age groups.

On post-hoc tests, mean values of MCHC in groups V and VI were significantly higher compared to group I.

IMS is one of the vendors awarded a contract in the MCHC CHIN, and also has a network already established in Illinois.

The program will use evidence-based curriculums and recruit participants via referrals from MCHC physicians and liaisons with schools, Head Start, public housing and churches.

89) between MCHC and Hb were observed in the female S.

18] In our study, MCH and MCHC values were within limits or on borderline in both the groups.

The reduction in levels of TEC, Hb, PCV, MCV, MCH, and MCHC are other concordant hematological alterations observed in the groups where lead acetate was administered, [25,26] resulting in microcytic hypochromic anemia.

The project, an outgrowth of a 2014 neighborhood improvement plan, was made possible through $650,000 in ongoing annual funding for MCHC from the Health Resources and Services Administration to open a clinic on the West Side.

Hemoglobin is the only hematology parameter with an international reference material, whereas other parameters such as RBC, hematocrit, MCV, MCH, MCHC, and platelets have reference methods only.

Anemia with reduced levels of Hb, TEC and MCHC as well as lymphocytopenia may be due to infection affects soft tissue such as lymphnodes.

A Interference with routine hemoglobin determinations may be suspected when the MCH and/or MCHC appear unlikely and can occur when lipid levels are elevated (lipemia).

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High MCHC: What Does It Mean?

Medically reviewed by Nancy Carteron, MD, FACR on October 25, 2017 — Written by Jill Seladi-Schulman, PhD

What is MCHC?

MCHC stands for mean corpuscular hemoglobin concentration. It’s a measure of the average concentration of hemoglobin inside a single red blood cell. MCHC is commonly ordered as part of a complete blood count (CBC) panel .

Why did my doctor order this test?

Usually, MCHC is ordered as part of a CBC panel. Your doctor can order this panel for any of the following reasons:

  • as part of a complete physical screen to evaluate your overall health
  • to aid in screening for or diagnosing various diseases or conditions
  • to monitor a condition once you’ve been diagnosed
  • to observe the effectiveness of a treatment

The CBC panel gives your doctor information about three types of cells in your blood: white blood cells, red blood cells, and platelets. The MCHC value is part of the red blood cell assessment.

What do the results mean?

MCHC is calculated by multiplying the hemoglobin result from the CBC panel by 100 and then dividing by the hematocrit result .

The reference range for MCHC in adults is 33.4–35.5 grams per deciliter (g/dL).

If your MCHC value is below 33.4 grams per deciliter, you have low MCHC. Low MCHC values occur if you have anemia due to iron deficiency . It can also indicate thalassemia . This is an inherited blood disorder in which you have fewer red blood cells and less hemoglobin present in your body. Learn more about low MCHC and its possible causes.

If your MCHC value is above 35.5 grams per deciliter, you have high MCHC.

What causes high MCHC?

A high MCHC value is often present in conditions where hemoglobin is more concentrated within your red blood cells. It can also occur in conditions where red blood cells are fragile or destroyed, leading to hemoglobin being present outside of the red blood cells. Conditions that can cause high MCHC calculations are:

Autoimmune hemolytic anemia

Autoimmune hemolytic anemia is a condition that occurs when your body develops antibodies that attack your red blood cells. When the condition has no determinable cause, it’s called idiopathic autoimmune hemolytic anemia .

Autoimmune hemolytic anemia can also develop along with another existing condition, such as lupus or lymphoma . Additionally, it can occur due to some medications, such as penicillin.

Your doctor can diagnose autoimmune hemolytic anemia using a blood test, such as a CBC panel. Other blood tests can also detect certain types of antibodies present in the blood or attached to red blood cells.

Symptoms of autoimmune hemolytic anemia include:

  • fatigue
  • paleness
  • weakness
  • jaundice , a yellowing of the skin and the whites of your eyes
  • chest pain
  • fever
  • fainting
  • abdominal discomfort, due to an enlarged spleen

If destruction of red blood cells is very mild, you may not experience any symptoms.

Corticosteroids such as prednisone are the first line of treatment for autoimmune hemolytic anemia. A high dose may be given initially and then gradually reduced over time. In cases where destruction of red blood cells is severe, blood transfusions or removal of the spleen ( splenectomy ) may be necessary.

Hereditary spherocytosis

Hereditary spherocytosis is a genetic disease affecting red blood cells. The genetic mutation affects the red blood cell membrane and makes it more fragile and prone to destruction.

In order to diagnose hereditary spherocytosis, your doctor will evaluate your family history. Typically, genetic testing isn’t needed, as the condition is inherited from a parent who has it. Your doctor will also use blood tests, such as a CBC panel, to learn more about the severity of the condition.

Hereditary spherocytosis has several forms, ranging from mild to severe. Symptoms can include:

  • anemia
  • jaundice
  • enlarged spleen
  • gallstones

Taking folic acid supplements or eating a diet high in folic acid can promote red blood cell production. In severe cases, blood transfusions or splenectomy may be needed. Additionally, if gallstones are a problem, all or part of the gallbladder may need to be removed .

Severe burns

People hospitalized with burns on greater than 10 percent of their body often have hemolytic anemia . A blood transfusion can help combat the condition.

The takeaway

MCHC is a measure of the average amount of hemoglobin inside of a single red blood cell, and it’s often ordered as part of a CBC panel.

You’ll have a high MCHC value if there’s an increased concentration of hemoglobin inside of your red blood cells. Additionally, conditions where hemoglobin is present outside of red blood cells due to red blood cell destruction or fragility can produce a high MCHC value.

Treatments for conditions causing high MCHC can include corticosteroids, splenectomy, and blood transfusions. Talk to your doctor about your blood test results. They’ll be able to answer your questions and describe your treatment plan.

Medically reviewed by Nancy Carteron, MD, FACR on October 25, 2017 — Written by Jill Seladi-Schulman, PhD

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We’ve got 25 definitions for MCHC »

What does MCHC stand for? 

What does MCHC mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: MCHC.


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MCHC

Mean Corpuscular Hemoglobin Concentration

Medical » Laboratory — and more…

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MCHC

Metropolitan Collegiate Hockey Conference

Sports » Hockey

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MCHC

Maternal Child Health Coalition

Community » Non-Profit Organizations

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MCHC

Mean Corpuscular Haemoglobin Concentration

Miscellaneous » Unclassified

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MCHC

Madison County Health Coalition

Medical » Healthcare

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MCHC

Maternal and Child Health Consortium

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MCHC

Middletown Community Health Center

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MCHC

Manchester Community Health Center

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MCHC

Mattapan Community Health Center

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MCHC

Mean Corpuscular Hemoglobin Content

Miscellaneous » Unclassified

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MCHC

microcrystalline Calcium hydroxyapatite compound

Miscellaneous » Unclassified

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MCHC

Munson Community Health Center

Medical » Healthcare

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MCHC

Maternal and Child Health Centre

Medical » Healthcare

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MCHC

Mean Cell Hemoglobin Concentration

Miscellaneous » Unclassified

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MCHC

Mountain Comprehensive Health Corporation

Business » Companies & Firms

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MCHC

Mountainlands Community Health Center

Medical » Healthcare

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MCHC

Mean Cell Haemoglobin Concentration

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MCHC

Metropolitan Chicago Healthcare Council

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MCHC

Montgomery County Hispanic Chamber

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MCHC

Mean Corpuscle Hemoglobin Concentration

Miscellaneous » Unclassified

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MCHC

Mean Corpuscular Haemoglobin Content

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MCHC

Mendocino Community Health Clinic

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MCHC

Michigan Collegiate Hockey Conference

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MCHC

Morris County Heritage Commission

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MCHC

Make Chavs History Campaign

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Popularity rank for the MCHC initials by frequency of use:

MCHC#1#19571#31140

Couldn’t find the full form or full meaning of MCHC?

Maybe you were looking for one of these abbreviations:

MCGP – MCGR – MCGS – MCH – MCHB – MChD – MCHE – MChem – MChemPhys – MCHES

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